CUSTOMER AREA
01 June 2017 - Case studies
S-Methoprene is an insect growth regulator that mimics the natural juvenile hormone in mosquitoes, inhibiting larval development. Larvicol Tablets contain 0.5% S-Methoprene and are typically used against Aedes aegypti, Aedes albopictus, and Culex pipiens. Efficacy trials have been conducted through laboratory and field studies.
Larvicol Tablets against Aedes aegypti in 15-liter containers
The doses of S-Methoprene applied were 0.005 and 0.01 ppm (1 tablet (2 g) / 2 m³ and 1 m³ of water), corresponding to 13.76 and 27.52 mg of tablet per 15 liters of water.

The results show that S-Methoprene at a concentration of 0.005 ppm provides 20 days of efficacy, while the higher concentration, 0.01 ppm, provides 30 days of efficacy.
Larvicol Tablets Against Culex pipiens in 200-Liter Drums
This study was a semi-field test conducted in 200-liter plastic drums (filled with 150 liters of water) placed outdoors. The doses of S-methoprene applied were 0.005 and 0.01 ppm (1 tablet (2 g) per 2 m³ and 1 m³ of water), corresponding to 137.6 mg and 275.2 mg of tablet per 150 liters of water.

While Aedes aegypti is more susceptible, Culex pipiens is less sensitive to S-methoprene.
As a result, since the goal of these tests was a 90% inhibition of emergence, the residual effectiveness of Larvicol Tablets was determined to last 14–15 days.

S-methoprene was applied at a dose of 0.010 ppm (1 tablet (2 g) per 1 m³ of water). This semi-field test was conducted in 200-liter tanks with four replicates and a control. The applied dose was one 0.4-gram tablet in 200 liters of water.
The results of the semi-field study demonstrate that for all three species, Larvicol Tablets can suppress the development of larvae into pupae or adults for approximately 4 weeks.
We believe that in the future, larvicide formulations based on S-methoprene will play an increasingly important role in mosquito control as a biorational biological control measure. Due to the European Biocidal Products Regulation—considering mosquito control—many restrictions are now in effect. As a result, public health and vector control in general are facing challenges, as the available substances and tools are becoming increasingly limited.
Freely translated from the study:
S-METHOPRENE INSECT GROWTH REGULATOR MOSQUITO LARVICIDES
RESULTS OF EFFICACY TRIALS
Dr. D. Bajomi *, N. Balázsdi-Szabó *, J. Schmidt *, J. Szilagyi *, B. Serrano #
* Babolna Bioenvironmental Centre Ltd., 1107-Budapest, Szallas u. 6., Hungary
# Laboratoire T.E.C., 1,rue Jules Védrines ZAC Maignon, 64600 Anglet, France