Efficacy Trials on S-Methoprene (Part Two)

01 June 2017 - Case studies

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Efficacy Trials on S-Methoprene (Part Two)

S-Methoprene is an insect growth regulator that mimics the natural juvenile hormone in mosquitoes, inhibiting larval development. Larvicol Tablets contain 0.5% S-Methoprene and are typically used against Aedes aegypti, Aedes albopictus, and Culex pipiens. Efficacy trials have been conducted through laboratory and field studies.

Studies with Larvicol Tablets

Larvicol Tablets against Aedes aegypti in 15-liter containers

The doses of S-Methoprene applied were 0.005 and 0.01 ppm (1 tablet (2 g) / 2 m³ and 1 m³ of water), corresponding to 13.76 and 27.52 mg of tablet per 15 liters of water.

The results show that S-Methoprene at a concentration of 0.005 ppm provides 20 days of efficacy, while the higher concentration, 0.01 ppm, provides 30 days of efficacy.

Larvicol Tablets Against Culex pipiens in 200-Liter Drums

This study was a semi-field test conducted in 200-liter plastic drums (filled with 150 liters of water) placed outdoors. The doses of S-methoprene applied were 0.005 and 0.01 ppm (1 tablet (2 g) per 2 m³ and 1 m³ of water), corresponding to 137.6 mg and 275.2 mg of tablet per 150 liters of water.

While Aedes aegypti is more susceptible, Culex pipiens is less sensitive to S-methoprene.

As a result, since the goal of these tests was a 90% inhibition of emergence, the residual effectiveness of Larvicol Tablets was determined to last 14–15 days.

Larvicol Tablets Against Aedes aegypti, Aedes albopictus, and Culex pipiens in 200-Liter Drums

Test Larvicol Compresse - risultati

S-methoprene was applied at a dose of 0.010 ppm (1 tablet (2 g) per 1 m³ of water). This semi-field test was conducted in 200-liter tanks with four replicates and a control. The applied dose was one 0.4-gram tablet in 200 liters of water.

The results of the semi-field study demonstrate that for all three species, Larvicol Tablets can suppress the development of larvae into pupae or adults for approximately 4 weeks.

We believe that in the future, larvicide formulations based on S-methoprene will play an increasingly important role in mosquito control as a biorational biological control measure. Due to the European Biocidal Products Regulation—considering mosquito control—many restrictions are now in effect. As a result, public health and vector control in general are facing challenges, as the available substances and tools are becoming increasingly limited.

Freely translated from the study:

S-METHOPRENE INSECT GROWTH REGULATOR MOSQUITO LARVICIDES

RESULTS OF EFFICACY TRIALS

Dr. D. Bajomi *, N. Balázsdi-Szabó *, J. Schmidt *, J. Szilagyi *, B. Serrano #

* Babolna Bioenvironmental Centre Ltd., 1107-Budapest, Szallas u. 6., Hungary

# Laboratoire T.E.C., 1,rue Jules Védrines ZAC Maignon, 64600 Anglet, France

01 June 2017 - Case studies

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